Summary report of the experiments conducted at Pouilly-le-Fort, near Melun, on the anthrax vaccination, 1881.
نویسندگان
چکیده
[Editorial note: The famous French microbiologist and chemist, Louis Pasteur, pioneered the use of bacterial vaccines for prevention of infectious diseases in animals and humans. One of his early successes was in the development of a vaccine for the agriculturally important disease anthrax, a vaccine that is still in use today for animals worldwide and humans in some countries. He demonstrated the effectiveness of his vaccines often with dramatic public trials, one of the most famous of which was the spectacle at the small French village of Pouilly-le-Fort in May 1881. This paper, translated from the original report in French, describes the set-up and outcome of this public test of anthrax vaccination. Pasteur uses the term virus in its nineteenth century context meaning any agent that transmits disease rather than in its more restricted modem sense. It is interesting to note that neither here nor elsewhere does Pasteur provide a description of the methods of preparation of his vaccine or other experimental details. He kept these confidential. Indeed, recent scholarship (G.L. Geison, The Private Science of Louis Pasteur, 1995) shows that his public pronouncements alluding to the success of his method for vaccine preparation are at odds with his laboratory notebooks, which show that he conducted these famous tests at Pouilly-le-Fort not with vaccine prepared by his method of oxygen attenuation, but with vaccine prepared by the bichromate inactivation methods of his competitor Jean-Joseph Henri Toussaint.]
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ورودعنوان ژورنال:
- The Yale Journal of Biology and Medicine
دوره 75 شماره
صفحات -
تاریخ انتشار 2002